Diagnosing IgG4-Related Lymphadenopathy

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IgG4-Related Lymphadenopathy

Lymphadenopathy is frequently observed in patients with immunoglobulin G4-related disease (IgG4-RD) and sometimes appears as the first manifestation of the disease. The diagnosis of IgG4-related lymphadenopathy is complicated owing to a great histological diversity, with at least 5 histological subtypes. Indeed, lymph node biopsy may be performed under the suspicion that the lymphadenopathy is ...

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IgG4-related prostatitis progressed from localized IgG4-related lymphadenopathy.

Immunoglobulin G4-related disease (IgG4-RD) is a recently described inflammatory disease involving multiple organs. Prostate involvement with IgG4-RD is very rare. In this report, we describe a case of IgG4-related prostatitis progressed from localized IgG4-related lymphadenopathy. This patient was present with urine retention symptoms. MRI and CT examination revealed the prostatic enlargement ...

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Persistent Lymphadenopathy due to IgG4-Related Disease

A 28-year-old healthy female presented to her primary care physician with lymphadenopathy, fatigue, malaise, and night sweats. Symptoms persisted despite conservative treatment and eventually the patient underwent multiple lymph node resections and a bone marrow biopsy before a diagnosis of IgG4-related disease (IgG4-RD) was made. IgG4-RD is a relatively new disorder first histopathologically r...

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Significance of lymphadenopathy in IgG4-related sclerosing disease and sarcoidosis.

journal.publications.chestnet.org patients). Similarly, determining the incidence of HIT in patients exposed to therapeutic treatment with heparin was supported by a paper reporting a retrospective study assessing the incidence of secondary thrombocytopenia recorded in the discharge boards of patients who were referred for a short stay in nonfederal US hospitals with a diagnostic code for throm...

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Abundance of IgG4+ plasma cells in isolated reactive lymphadenopathy is no indication of IgG4-related disease.

OBJECTIVES IgG4-related disease is a recently recognized condition that can be associated with lymphadenopathy, with several histologic patterns and increased absolute number and ratio of immunoglobulin G4 (IgG4)-positive plasma cells. However, these findings are considered to be not exclusively specific for IgG4-related disease. METHODS The occurrence of the histologic patterns reported in p...

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ژورنال

عنوان ژورنال: American Journal of Clinical Pathology

سال: 2012

ISSN: 0002-9173,1943-7722

DOI: 10.1093/ajcp/138.suppl1.039